专利名称:N-ACETYL THIENMYCIN
发明人:J.S. KAHAN,F.M. KAHAN,R.T.
GOEGELMAN,E.O. STTAPLEY,S. HERNANDEZ 申请号:AU1964676
申请日:19761115
公开号:AU514309B2
公开日:
19810205tami chynn
专利内容由知识产权出版社提供
摘要:The microorganism Streptomyces cattleya, preferably the strain NRRL 8057, is cultivated under submerged aerobic conditions in an aqueous nutrient medium containing assimilable C and N sources as well as inorganic salts. N-Acetylthienamycin is obtained. Non-toxic, pharmaceutically acceptable salts of N-acetylthienamycin can be obtained by reaction with inorganic or organic bases. N-acetylthienamycin and its salts show remarkable antibiotic properties and are active against a wide range of pathogens as well as against resistant strains of particular microorganisms. The antibiotic is active against Gram-positive and -negative bacteria and is suitable for use in human and veterinary medicine and as antibacterial agent for commercial and industrial purposes.
申请人:MERCK & CO. INC.
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