Mosnodenvir 阻断病毒复制复合体内的 NS3-NS4B 相互作⽤。Mosnodenvir 在⼩⿏体内显⽰出⽪摩尔到低纳
[1]. Ackaert O, et al. Safety, tolerability and pharmacokinetics of JNJ-1802, a pan-serotype dengue direct antiviral small molecule, in a
Phase 1, double-blind, randomized, dose-escalation study in healthy volunteers. Clin Infect Dis. 2023 May 10:ciad284.
[2]. Goethals O, et al. Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates. Nature. 2023 Mar;615(7953):678-686.
Caution: Product has not been fully validated for medical applications.
For research use only.
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kingston mon1/1Master of Bioactive Molecules —您⾝边的抑制剂⼤师
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